Reading Jon Eisen’s blog this week I was rather taken with this post about LigerCat. LigerCat is an online tool that searches pubmed for whatever you ask it to, and displays a cloud of the MeSH terms (keywords attached to articles) associated with the pubmed results. It also shows a neat bar chart of article counts by year.
Since I’ve just been introduced to enteroaggregative E. coli thanks to the German E. coli outbreak, I thought I’d search for “Enteroaggregative E. coli”… this is the result.
I think this shows quite nicely that (at least according to the literature) this organism is defined by adhesion, normally associated with diarrhea in children and babies and commonly tested for by PCR.
According to this it was first described as enteroaggregative E. coli in 1989 and has been the subject of some attention, but not a lot, ever since (~15 articles per year):
The picture is quite different for “Shiga toxin“, most associated with E. coli O157 and hemolytic-uremic syndrome, with first mention in 1942 and a mass of interest since the 1980s, now with >200 papers each year: